HTC-15 - Conference Programme
The conference will include 5 plenary lectures, 16 keynote lectures, 8 tutorial lectures, 48 oral presentations, and daily poster sessions. The programme includes sessions on Big Data, Fundamentals and Exploiting Separation Science, (R)evolutions in Biopharmaceutical Analysis, Food and Drink, Environmental, Comprehensive Chromatography and many more topics relevant to the separation scientist. There will also be a dedicated early-career researchers (ECR) session, with 24 ECR presentations. We have successfully secured sponsorship for ECRs and will be able to offer free registration for presenters in this session, so please apply for this support.
Click here for conference registrationRunning alongside the symposium will be a large focused technical exhibition where companies will present the latest developments in instrumentation, software and applications.
HTC-15 Conference Programme - Day1 (24th January 2018)
| 08:45 - 09:00 | HTC-15 Opening Ceremony | ||
| 09:00 - 09:50 | Plenary: Why Do We Still Use Silica KNOX Award Lecture by Prof Peter Myers, University of Liverpool (Lower Hall) | ||
| 09:50 - 10:30 | Coffee Break & Exhibition | ||
| Time | Lower Hall | Ferrier Hall | Room D |
|---|---|---|---|
| Session 1: Exploiting Separation Science (Chair: Tom Lynch) |
Session 2: (R)evolutions in Biopharmaceutical Analysis (KVCV) (Chair: Deirdre Cabooter) | Session 3: Fundamentals in Separation Science (Chair: Paul Ferguson) | |
| 10:30 - 11:00 | Keynote: Separation science and its use for generating data, information and understanding Presenter: Hans Gerd Janssen, Unilever Research and University of Amsterdam |
Keynote: Recent advances in the analysis of protein biopharmaceuticals Presenter: Koen Sandra, Research Institute for Chromatography |
Tutorial: A tutorial on the fundamentals of hydrophilic interaction chromatography (HILIC) for pharmaceutical analysis Presenter: James Heaton, Pfizer Ltd |
| 11:00 - 11:20 | Presentation: Novel ways to introduce the traditional salt based chromatography technique of Ion Exchange Chromatography of biopharmaceutical proteins into High Resolution Mass Spectrometry Presenter: Florian Füssl , Thermo Fisher Scientific |
Presentation: Prototyping of a microfluidic multilayer modulator chip for multi-dimensional separations Presenter: Jelle De Vos, Vrije Universiteit Brussel |
Presentation: Probing selectivity of mixed-mode reversed-phase / weak-anion-exchange columns for small-molecule separations in liquid chromatography Presenter: José Luís Dores-Sousa, Vrije Universiteit Brussel |
| 11:20 - 11:40 | Presentation: Hyphenated microdialysis and chromatography to monitoring protein free drug for pharmacokinetic study in rat Presenter: Tung-Hu Tsai, National Yang-Ming University |
Presentation: Advancing the analytical toolbox using shotgun lipidomics for lipid modifying enzymes Presenter: Dr Erwin Kaal, DSM |
Presentation: Understanding the possibilities of solvent-assisted post-column refocusing to enhance detection limits in 1-D and 2-D LC Presenter: Vincent Pepermans, Vrije Universiteit Brussel |
| 11:40 - 12:00 | Presentation: Expanding the Application of Thermal Desorber Devices towards Dynamic Headspace Gas Chromatography for the Determination of Residual Solvents Presenter: Erwin Adams, Pharmaceutical Analysis - KU Leuven |
Presentation: Lipidomics by UHPL-CQTOF-MS/MS with Data-Independent Acquisition and Clinical Applications Presenter: Michael Laemmerhofer, University of Tuebingen |
Presentation: Investigating the potential for improved temperature responsive separations in liquid chromatography Presenter: Mathijs Baert, Ghent University |
| 12:00-14:00 | Lunch Break, Vendor Seminars, Exhibition & Posters | ||
| Session 4: Fundamentals in Separation Science (KVCV) (Chair: Sebastiaan Eeltink) | Session 5: Advances in Clinical Analysis (Chair: Dave Perrett) |
Session 6: Interfacing and Ionisation (Chair: Ruth Godfrey) |
|
| 14:00 - 14:30 | Keynote:Recent Progress in the Development of Perfectly Ordered Separation Media Presenter: Gert Desmet, Vrije Universiteit Brussel |
Keynote: UPLC-MS for Metabolic Phenotyping: Advantages, Assays and Applications Presenter: Elizabeth Want, Imperial College London |
Tutorial: Interfacing LC to MS Presenter: Julie Herniman, University of Southampton |
| 14:30 - 14:50 | Presentation: Considerations for the use of ultra-high pressures in liquid chromatography for 2.1mm inner diameter columns Presenter: Ken Broeckhoven, Vrije Universiteit Brussel |
Presentation: Opportunities for ultra-rapid LC-MS/MS in high-throughput bioanalysis Presenter: Lewis Couchman, Analytical Services International (ASI) Ltd |
Presentation: Characterization of complex polyether polyols using comprehensive two-dimensional liquid chromatography hyphenated with high resolution mass spectrometry (LCxLC-HRMS) Presenter: Gino Groeneveld, University of Amsterdam |
| 14:50 - 15:10 | Presentation: Matching 1st and 2nd dimension chemistries in the 2D-LC. Active Solvent Modulation Presenter: Konstantin Shoykhet, Agilent Technologies |
Presentation: Apolipoproteins, non-polar lipids, polar lipids and lipoprotein particle numbers. Can we measure them all on large number of samples? Presenter: Zsuzsanna Kuklenyik, Centers for Disease Control and Prevention |
Presentation: The comparison of Unispray and Electrospray for the ionization of neuropeptides Presenter: Yannick Van Wanseele, Vrije Universiteit Brussel |
| 15:10 - 15:30 | Presentation: Kinetics and mass transfer phenomena in modern chiral stationary phases Presenter: Alberto Cavazzini, University of Ferrara |
Presentation: Detection and differentiation of botulinum neurotoxins for the diagnosis and prevention of botulism Presenter: John Barr, Centers for Disease Control and Prevention (CDC) |
Presentation: Sequential Three-Dimensional Gas Chromatography with Accurate Mass Spectrometry: A Novel Tool for High-Resolution Characterization of Multicomponent Samples Presenter: Dandan Yan, Unversity of Tasmania |
| 15:30 - 16:00 | Coffee Break, Exhibition & Posters | ||
| Session 7: High throughput versus High Efficiency Separations (CS) (Chair: Paul Ferguson) | Session 8: Exploiting Separation Science and Mass Spectrometry (Chair: Lewis Couchman) | Session 9: Microfluidics & Flow Process Technology (Chair: Sebastiaan Eeltink) | |
| 16:00 - 16:30 | Keynote: High temperature chromatography: the winning solution allowing both throughput and efficiency? Presenter: Frederic Lynen, University of Ghent |
Keynote: Supercritical Fluid Chromatography - Mass Spectrometry: Robust, Reliable and Required Presenter: John Langley, University of Southampton |
Tutorial: Flow chemistry: A synthetic chemist's perspective Presenter: Anna Slater, University of Liverpool |
| 16:30 - 16:50 | Presentation: Strategies to Optimize Throughput in 2D-LC Presenter: Monika Dittmann, Agilent Technologies |
Presentation: Possibilities of modern size-exclusion chromatography for therapeutic proteins; feasibility assessment for future mass spectrometry hyphenation Presenter: Szabolcs Fekete, University of Geneva |
Presentation: Chemically Sensitive Online Detectors for SEC – current advances for SEC-MR-NMR and SEC-QCL-IR Presenter: Johannes Höpfner, Karlsruhe Institute of Technology (KIT) |
| 16:50 - 17:10 | Presentation: Fast, efficient and selective: separation science for modern organic synthetic chemistry Presenter: Tomas Leek, AstraZeneca |
Presentation: Separation of isomeric metabolites of carbamazepine by liquid chromatography and high resolution accurate mass Presenter: Joanne Roberts, Glasgow Caledonian University |
Presentation: Comprehensive Two-Dimensional Liquid Chromatography Coupled to Triple-Detection for Characterization of Branched Polymers Presenter: Nico Apel, Fraunhofer LBF |
| 17:10 - 17:30 | Presentation: Generic Reverse Phase Chromatography... Speed, performance... or both? Presenter: Bob Boughtflower, GSK |
Presentation: Quantitative drug metabolite profiling without authentic standards or radiolabels using LC-ICP-MS Presenter: Filip Cuyckens, Janssen R&D |
Presentation: Chromatographic strategies combining RPLC, mixed-mode HPLC and SFC coupled to MS for impurity profiling of drugs candidates Presenter: Elise Lemasson, Institut de Chimie Organique et Analytique(ICOA) |
| 17:30-18:30 | Happy Hour Drinks Reception Sponsored by Leco Instruments | ||
| 19:30 | Beer Degustation Social at The Yard (Brains) | ||
HTC-15 Conference Programme - Day2 (25th January 2018)
| 08:00 - 08:45 | Breakfast workshop: Professional development and careers [Dayna Mason (RSC CPD & outreach in Cardiff) & Deirdre Cabooter] | ||
| 08:55 - 09:00 | HTC-15 Announcements | ||
| 09:00 - 09:50 | Plenary: Transforming Big Data Into Big Analysis: The Power of Finding Use-Value In Your Data by Eric Little, OSTHUS (Lower Hall) | ||
| 09:50 - 10:30 | Coffee Break & Exhibition | ||
| Time | Lower Hall | Ferrier Hall | Room D |
|---|---|---|---|
| Session 10: SSG session (Chair: John Langley) | Session 11: Big Data - What do we do with it? (Chair: Arun Sen) | Session 12: Separations by shape: Instrumentation (Chairs: Alison Ashcroft & Anton Calabrese) | |
| 10:30 - 11:00 | Keynote: Advancing hydrophobic interaction chromatography methods to characterize biotechnology enzyme mixtures and to profile biotherapeutics Presenter: Sebastiaan Eeltink, Vrije Universiteit Brussel |
Keynote: Clinical Lipidomic Quantitation Based on Mass Spectrometry: Case Study of Pancreatic Cancer Presenter: Michal Holcapek, University of Pardubice |
Tutorial: Separation and characterisation by ion mobility-mass spectrometry Presenter: Antonio Calabrese, University of Leeds |
| 11:00 - 11:20 | Presentation: Methodologies to determine b-term coefficients revisited Presenter: Deirdre Cabooter, University in Leuven |
Presentation: Replicates of Complex Mixtures in Ultra-High Resolution Mass Spectrometry Could Help Pave The Way to Big Data Presenter: Remy Gavard, University of Warwick |
Presentation: FAIMS and fortune Presenter: Christianne Wicking, BP |
| 11:20 - 11:40 | Presentation: UHPLC quantitation and identity confirmation in drug development with a multi-detector approach Presenter: Frank Steiner, Thermo Fisher Scientific |
Presentation: Big Data - When Less is More Presenter: Benjamin Woolford-Lim, GlaxoSmithKline |
Presentation: Topology discrimination of saponin ions by Hyphenated Mass Spectrometry techniques and computational chemistry Presenter: Corentin Decroo, Umons |
| 11:40 - 12:00 | Presentation: LCGC innovation award 2018 | Presentation: Looking Inside the Black Box of Machine Learning Methods: Applications in Analytical Chemistry Presenter:Phil Kay, JMP, SAS Institute |
Presentation: Better Living Through (Flavor) Chemistry: Vacuum Ultraviolet Spectroscopy as a New Tool for GC Analysis of Terpenes in Flavors and Fragrances Presenter: Alex Hodgson, VUV Analytics |
| 12:00-14:00 | Lunch Break, Vendor Seminars, Exhibition & Posters | ||
| Session 13: Green Separations (Chair: Paul Ferguson) |
Session 14: Big Data Chemometrics and Method development (In-Silico) (KVCV) (Chair: Ken Broeckhoven) |
Session 15: Approaches to maximising analytical data (Chair: Scott Fletcher) | |
| 14:00 - 14:30 | Keynote: 50 shades of Green SFC Presenter: Caroline West, University of Orleans |
Keynote: A paradigm shift for (big) data analysis in chromatography: on the use of Bayesian statistics Presenter: Gabriel Vivo Truyols, Tecnometrix |
Tutorial: Maximising analytical data by understanding the implications of uncertainty Presenter: Chris Hopley, LGC |
| 14:30 - 14:50 | Presentation: Can CE-MS improve the detection of peptides and intact proteins and in biological samples? Presenter: Stephen Lock, Sciex |
Presentation: Chromatographic fingerprints: chemometrics and application in method development Presenter: Yvan Vanderheyden, Vrije Universiteit Brussel |
Presentation: Data to decision: efficient processing of complex petroleomics data Presenter: Samuel Ellick, University of Bristol |
| 14:50 - 15:10 | Presentation: UHPSFC-MS of a Range of Steroidal Compounds Presenter: Julie Herniman, University of Southampton |
Presentation: Use of different computer-aided method development software in late stages across global sites in pharmaceutical industry Presenter: Kai Chen, Janssen Pharmaceutical Companies of Johnson & Johnson |
Presentation: Characterization of Small Heterogeneities in Polymers by Analysis of UPLC/ESI-MS Reconstructed Ion Chromatograms Presenter: Ruben Epping, Bundesanstalt für Materialforschung und -prüfung (BAM) |
| 15:10 - 15:30 | Presentation: Online extraction and determination of carotenoids from food sample by means of supercritical fluid extraction-supercritical fluid chromatography-mass spectrometry Presenter: Mariosimone Zoccali, University of Messina |
Presentation: Structure driven prediction of retention :Improvement of accuracy Presenter: Roman Szucs, Pfizer |
Presentation: Quantitative proteomics for molecular diagnostics of public health Presenter: Jack Rice, University of Bath |
| 15:30 - 16:00 | Coffee Break & Exhibition | ||
| Session 16: Ion Mobility - Mass Spectrometry (BMSS) (Chair: Alison Ashcroft) | Session 17: Screening Enviroment Pollutants, what can the data tell us? (Chair: Graham Mills) | Session 18: Separations by shape: Further applications of chromatography (Chair: Caroline West) |
|
| 16:00 - 16:30 | Keynote: Ion mobility mass spectrometry - leveraging rich data on the gas-phase ion to separate and assign Presenter: Cris Lapthorn, GSK |
Keynote: Urban water profiling to inform the state of the environment and public health Presenter: Barbara Kasprzyk-Hordern, University of Bath |
Tutorial: Analysis of food products using advanced analytical techniques Presenter: Paola Dugo, University of Messina |
| 16:30 - 16:50 | Presentation: Understanding phosphorylation-mediated effects on NF-κB interactions using IM-MS Presenter: Claire Eyers, University of Liverpool |
Presentation: Suspect screening of aquatic environmental matrices using high resolution analysis and in silico tools for broad scope tentative contaminant identification Presenter: Leon Barron, King's College London |
Presentation: On-line coupling of RPLC and chiral SFC for the analysis of pharmaceutical compounds Presenter: Marion Iguiniz, Université de Lyon |
| 16:50 - 17:10 | Presentation: An Advanced Cyclic Ion Mobility - Mass Spectrometry System Presenter: Kevin Giles, Waters Corporation |
Presentation: Screening of environmental passive sampling extracts using LC Q-TOF-MS in data-independent acquisition mode Presenter: Anthony Gravell, Natural Resources Wales |
Presentation: Enhanced resolution of stereoisomers through Stationary phase optimized selectivity liquid and supercritical chromatography (SOS-LC and SOS-SFC) Presenter: Ravindra Hegade, Ghent University |
| 17:10 - 17:30 | Presentation: FAIMS mass spectrometry for the analysis of peptides and proteins Presenter: Helen Cooper, University of Birmingham |
Presentation: Combining high-capacity sorptive extraction with Thermal desorption pre-concentration for analysis of (S)VOCs in environmental samples Presenter: Lara Kelly, Markes International Ltd |
Presentation:
LC-MS/MS chiral ananlysis of chloramphencicol in the environment Presenter: Felicity Elder, University of Bath |
| 19:15 | Gala Dinner Event | ||
HTC-15 Conference Programme - Day3 (26th January 2018)
| 08:55 - 09:00 | HTC-15 Announcements | ||
| 09:00 - 09:50 | Plenary: Tuulia Hyotylainen - Hyphenated Techniques for comprehensive analysis of all metabolites in biological systems to describe metabolic changes caused by disease, environmental, nutritional, or genetic factors (Lower Hall) | ||
| 09:50 - 10:30 | Coffee Break & Exhibition | ||
| Time | Lower Hall | Ferrier Hall | Room D |
|---|---|---|---|
| Session 19: Automating Complex Sample Workflows (Chair: Bob Boughtflower) | Session 20: Comprehensive Chromatography - The State of the art (Chair: Hans Gerd Janssen) | Session 21: Energy & the Environment (Chair: Sam Whitmarsh) |
|
| 10:30 - 11:00 | Keynote: Laboratory Automation: The Rise of the Machines Presenter: Scott Summerfield, GSK |
Keynote: Flow Modulated Two-dimensional Gas Chromatography Coupled to Tandem Mass Spectrometry for "Comprehensive" characterization of Complex Samples Presenter: Luigi Mondello, University of Messina |
Tutorial: Environmental health and well-being: diagnostics with hyphenated gas chromatography Presenter: John Dean, Northumbria University |
| 11:00 - 11:20 | Presentation: Automated sample preparation: the missing hyphen to hypernation Presenter: Camilla Liscio, Anatune |
Presentation: Applicability of retention modelling in hydrophilic-interaction liquid chromatography for algorithmic optimization programs with gradient-scanning techniques Presenter: Bob Pirok, University of Amsterdam |
Presentation: Fingerprint characterization of bio-oil from the pyrolysis of African palm and its esterification product Presenter: Diana Palacio, University of Warwick |
| 11:20 - 11:40 | Presentation: Solid Phase Micro-Extraction - Breaking Free from Total Concentration Analysis Presenter: Sheelan Ahmad, GlaxoSmithKline |
Presentation: All Ion Differential Analysis in Product Control Applications using GC/MS and Comprehensive GCxGC/MS Presenter: Marco Ruijken, MsMetrix |
Presentation: Mass Spectrometric Investigation of Compounds of Interest to the Chemical Investigation Programme (CIP) within Environmental Matrices: Homogenate Analysis Presenter: Rachel Townsend, Swansea University |
| 11:40 - 12:00 | Presentation: Analytical developments in sample preparation to reliably measure the emission of volatiles from materials in a high-throughput fashion Presenter: An Adams, Dow |
Presentation: Detection of bacteriologically produced hydrogen sulphide using SHS-MCC-GC-IMS Presenter: John Dean, Northumbria University |
Presentation: Petroleomic Depth Profiling of Staten Island Soil by GC and FT-ICR MS Presenter: Mary Thomas, University of Warwick |
| 12:00 - 12:40 | Lunch Break & Exhibition | ||
| Session 22: Analysis of Complex Energy Products (Chair: Tom Lynch) | Session 23: Advanced Analysis of Food and Beverages (Chair: Lewis Jones) | Session 24: Life science & pharma (Chair: Melissa Hanna-Brown) |
|
| 12:40 - 13:10 | Keynote: Thermal Analysis in hyphenation with mass spectrometry as a versatile tool for the analysis of complex and high boiling petroleum products Presenter: Thomas Gröger, helmholtz Zentrum München GmbH |
Keynote: Exploiting comprehensive two-dimensional liquid chromatography in food analysis Presenter: Paola Dugo, University of Messina |
Tutorial: LC-MS small molecule quantitation: a short tutorial of best practice Presenter: Ruth Godfrey, Swansea University |
| 13:10 - 13:30 | Presentation: Direct infusion MS - who needs hyphenation anyway? Presenter: Sam Whitmarsh, BP |
Presentation: Can Gas Chromatography - Olfactometry Determine the Importance of Volatile Organic Chemical to Food and Beverage Odour? Presenter: Lewis Jones, Sensient Flavours |
Presentation: From GC-MS to LC-MS/MS: Further Advances in Adrenal Cancer Diagnosis Presenter: Angela Taylor, University of Birmingham |
| 13:30 - 13:50 | Presentation: Fast and efficient group-type analysis of hydrocarbons by GCxGC Presenter: Laura McGregor, SepSolve Analytical |
Presentation: Rapid evaporative ionization mass spectrometry for high throughput screening in food analysis: the case of boar taint Presenter: Sara Stead, Waters Corporation |
Presentation: Green Bioanalytical Analysis of Voriconazole and Tadalafil by HPLC Presenter: Aysegul Dogan, Hacettepe University |
| 13:50 - 14:10 | Presentation: Recent Advances in the Analysis of Petroleum-based Fuels using Gas Chromatography-Vacuum Ultraviolet Spectroscopy Presenter: James Diekmann, VUV Analytics |
Presentation: Monitoring the effect of post-harvest storage on fruit quality by TD-GC×GC-TOF MS Presenter: Natasha/D. Spadafora, University of Calabria/Markes International |
Presentation: Improving Untargeted Metabolomics with Ion Chromatography-Mass Spectrometry Presenter: John Walsby-Tickle, University of Oxford |
| 14:10 - 14:30 | Flash Poster Presentations | ||
| 14:30 - 15:20 | Of mice, sex and mass spectrometry Plenary by Rob Beynon (Chair: John Langley) (Lower Hall) | ||
| 15:20 - 16:10 | Multi-dimensional liquid chromatography of complex mixtures Plenary by Peter Schoenmakers (Chair: Frederic Lynen) (Lower Hall) | ||
| 16:10 - 16:30 | Awards | ||
| 16:30 | Farewell Event | ||
