HTC-15 - Conference Programme

The conference will include 5 plenary lectures, 16 keynote lectures, 8 tutorial lectures, 48 oral presentations, and daily poster sessions. The programme includes sessions on Big Data, Fundamentals and Exploiting Separation Science, (R)evolutions in Biopharmaceutical Analysis, Food and Drink, Environmental, Comprehensive Chromatography and many more topics relevant to the separation scientist. There will also be a dedicated early-career researchers (ECR) session, with 24 ECR presentations. We have successfully secured sponsorship for ECRs and will be able to offer free registration for presenters in this session, so please apply for this support.

Click here for conference registration

Running alongside the symposium will be a large focused technical exhibition where companies will present the latest developments in instrumentation, software and applications.

HTC-15 Conference Programme - Day1 (24th January 2018)
08:45 - 09:00HTC-15 Opening Ceremony
09:00 - 09:50Plenary: Why Do We Still Use Silica KNOX Award Lecture by Prof Peter Myers, University of Liverpool (Lower Hall)
09:50 - 10:30Coffee Break & Exhibition
Time Lower Hall Ferrier Hall Room D
  Session 1: Exploiting Separation Science
(Chair: Tom Lynch)
Session 2: (R)evolutions in Biopharmaceutical Analysis (KVCV) (Chair: Deirdre Cabooter) Session 3: Fundamentals in Separation Science (Chair: Paul Ferguson)
10:30 - 11:00 Keynote: Separation science and its use for generating data, information and understanding
Presenter: Hans Gerd Janssen, Unilever Research and University of Amsterdam
Keynote: Recent advances in the analysis of protein biopharmaceuticals
Presenter: Koen Sandra, Research Institute for Chromatography
Tutorial: A tutorial on the fundamentals of hydrophilic interaction chromatography (HILIC) for pharmaceutical analysis
Presenter: James Heaton, Pfizer Ltd
11:00 - 11:20 Presentation: Novel ways to introduce the traditional salt based chromatography technique of Ion Exchange Chromatography of biopharmaceutical proteins into High Resolution Mass Spectrometry
Presenter: Florian Füssl , Thermo Fisher Scientific
Presentation: Prototyping of a microfluidic multilayer modulator chip for multi-dimensional separations
Presenter: Jelle De Vos, Vrije Universiteit Brussel
Presentation: Probing selectivity of mixed-mode reversed-phase / weak-anion-exchange columns for small-molecule separations in liquid chromatography
Presenter: José Luís Dores-Sousa, Vrije Universiteit Brussel
11:20 - 11:40 Presentation: Hyphenated microdialysis and chromatography to monitoring protein free drug for pharmacokinetic study in rat
Presenter: Tung-Hu Tsai, National Yang-Ming University
Presentation: Advancing the analytical toolbox using shotgun lipidomics for lipid modifying enzymes
Presenter: Dr Erwin Kaal, DSM
Presentation: Understanding the possibilities of solvent-assisted post-column refocusing to enhance detection limits in 1-D and 2-D LC
Presenter: Vincent Pepermans, Vrije Universiteit Brussel
11:40 - 12:00 Presentation: Expanding the Application of Thermal Desorber Devices towards Dynamic Headspace Gas Chromatography for the Determination of Residual Solvents
Presenter: Erwin Adams, Pharmaceutical Analysis - KU Leuven
Presentation: Lipidomics by UHPL-CQTOF-MS/MS with Data-Independent Acquisition and Clinical Applications
Presenter: Michael Laemmerhofer, University of Tuebingen
Presentation: Investigating the potential for improved temperature responsive separations in liquid chromatography
Presenter: Mathijs Baert, Ghent University
12:00-14:00Lunch Break, Vendor Seminars, Exhibition & Posters
  Session 4: Fundamentals in Separation Science (KVCV) (Chair: Sebastiaan Eeltink) Session 5: Advances in Clinical Analysis
(Chair: Dave Perrett)
Session 6: Interfacing and Ionisation
(Chair: Ruth Godfrey)
14:00 - 14:30 Keynote:Recent Progress in the Development of Perfectly Ordered Separation Media
Presenter: Gert Desmet, Vrije Universiteit Brussel
Keynote: UPLC-MS for Metabolic Phenotyping: Advantages, Assays and Applications
Presenter: Elizabeth Want, Imperial College London
Tutorial: Interfacing LC to MS
Presenter: Julie Herniman, University of Southampton
14:30 - 14:50 Presentation: Considerations for the use of ultra-high pressures in liquid chromatography for 2.1mm inner diameter columns
Presenter: Ken Broeckhoven, Vrije Universiteit Brussel
Presentation: Opportunities for ultra-rapid LC-MS/MS in high-throughput bioanalysis
Presenter: Lewis Couchman, Analytical Services International (ASI) Ltd
Presentation: Characterization of complex polyether polyols using comprehensive two-dimensional liquid chromatography hyphenated with high resolution mass spectrometry (LCxLC-HRMS)
Presenter: Gino Groeneveld, University of Amsterdam
14:50 - 15:10 Presentation: Matching 1st and 2nd dimension chemistries in the 2D-LC. Active Solvent Modulation
Presenter: Konstantin Shoykhet, Agilent Technologies
Presentation: Apolipoproteins, non-polar lipids, polar lipids and lipoprotein particle numbers. Can we measure them all on large number of samples?
Presenter: Zsuzsanna Kuklenyik, Centers for Disease Control and Prevention
Presentation: The comparison of Unispray and Electrospray for the ionization of neuropeptides
Presenter: Yannick Van Wanseele, Vrije Universiteit Brussel
15:10 - 15:30 Presentation: Kinetics and mass transfer phenomena in modern chiral stationary phases
Presenter: Alberto Cavazzini, University of Ferrara
Presentation: Detection and differentiation of botulinum neurotoxins for the diagnosis and prevention of botulism
Presenter: John Barr, Centers for Disease Control and Prevention (CDC)
Presentation: Sequential Three-Dimensional Gas Chromatography with Accurate Mass Spectrometry: A Novel Tool for High-Resolution Characterization of Multicomponent Samples
Presenter: Dandan Yan, Unversity of Tasmania
15:30 - 16:00Coffee Break, Exhibition & Posters
  Session 7: High throughput versus High Efficiency Separations (CS) (Chair: Paul Ferguson) Session 8: Exploiting Separation Science and Mass Spectrometry (Chair: Lewis Couchman) Session 9: Microfluidics & Flow Process Technology (Chair: Sebastiaan Eeltink)
16:00 - 16:30 Keynote: High temperature chromatography: the winning solution allowing both throughput and efficiency?
Presenter: Frederic Lynen, University of Ghent
Keynote: Supercritical Fluid Chromatography - Mass Spectrometry: Robust, Reliable and Required
Presenter: John Langley, University of Southampton
Tutorial: Flow chemistry: A synthetic chemist's perspective
Presenter: Anna Slater, University of Liverpool
16:30 - 16:50 Presentation: Strategies to Optimize Throughput in 2D-LC
Presenter: Monika Dittmann, Agilent Technologies
Presentation: Possibilities of modern size-exclusion chromatography for therapeutic proteins; feasibility assessment for future mass spectrometry hyphenation
Presenter: Szabolcs Fekete, University of Geneva
Presentation: Chemically Sensitive Online Detectors for SEC – current advances for SEC-MR-NMR and SEC-QCL-IR
Presenter: Johannes Höpfner, Karlsruhe Institute of Technology (KIT)
16:50 - 17:10 Presentation: Fast, efficient and selective: separation science for modern organic synthetic chemistry
Presenter: Tomas Leek, AstraZeneca
Presentation: Separation of isomeric metabolites of carbamazepine by liquid chromatography and high resolution accurate mass
Presenter: Joanne Roberts, Glasgow Caledonian University
Presentation: Comprehensive Two-Dimensional Liquid Chromatography Coupled to Triple-Detection for Characterization of Branched Polymers
Presenter: Nico Apel, Fraunhofer LBF
17:10 - 17:30 Presentation: Generic Reverse Phase Chromatography... Speed, performance... or both?
Presenter: Bob Boughtflower, GSK
Presentation: Quantitative drug metabolite profiling without authentic standards or radiolabels using LC-ICP-MS
Presenter: Filip Cuyckens, Janssen R&D
Presentation: Chromatographic strategies combining RPLC, mixed-mode HPLC and SFC coupled to MS for impurity profiling of drugs candidates
Presenter: Elise Lemasson, Institut de Chimie Organique et Analytique(ICOA)
17:30-18:30Happy Hour Drinks Reception Sponsored by Leco Instruments
Leco instruments
19:30Beer Degustation Social at The Yard (Brains)
HTC-15 Conference Programme - Day2 (25th January 2018)
08:00 - 08:45Breakfast workshop: Professional development and careers [Dayna Mason (RSC CPD & outreach in Cardiff) & Deirdre Cabooter]
08:55 - 09:00HTC-15 Announcements
09:00 - 09:50Plenary: Transforming Big Data Into Big Analysis: The Power of Finding Use-Value In Your Data by Eric Little, OSTHUS (Lower Hall)
09:50 - 10:30Coffee Break & Exhibition
Time Lower Hall Ferrier Hall Room D
  Session 10: SSG session (Chair: John Langley) Session 11: Big Data - What do we do with it? (Chair: Arun Sen) Session 12: Separations by shape: Instrumentation (Chairs: Alison Ashcroft & Anton Calabrese)
10:30 - 11:00 Keynote: Advancing hydrophobic interaction chromatography methods to characterize biotechnology enzyme mixtures and to profile biotherapeutics
Presenter: Sebastiaan Eeltink, Vrije Universiteit Brussel
Keynote: Clinical Lipidomic Quantitation Based on Mass Spectrometry: Case Study of Pancreatic Cancer
Presenter: Michal Holcapek, University of Pardubice
Tutorial: Separation and characterisation by ion mobility-mass spectrometry
Presenter: Antonio Calabrese, University of Leeds
11:00 - 11:20 Presentation: Methodologies to determine b-term coefficients revisited
Presenter: Deirdre Cabooter, University in Leuven
Presentation: Replicates of Complex Mixtures in Ultra-High Resolution Mass Spectrometry Could Help Pave The Way to Big Data
Presenter: Remy Gavard, University of Warwick
Presentation: FAIMS and fortune
Presenter: Christianne Wicking, BP
11:20 - 11:40 Presentation: UHPLC quantitation and identity confirmation in drug development with a multi-detector approach
Presenter: Frank Steiner, Thermo Fisher Scientific
Presentation: Big Data - When Less is More
Presenter: Benjamin Woolford-Lim, GlaxoSmithKline
Presentation: Topology discrimination of saponin ions by Hyphenated Mass Spectrometry techniques and computational chemistry
Presenter: Corentin Decroo, Umons
11:40 - 12:00 Presentation: LCGC innovation award 2018 Presentation: Looking Inside the Black Box of Machine Learning Methods: Applications in Analytical Chemistry
Presenter:Phil Kay, JMP, SAS Institute
Presentation: Better Living Through (Flavor) Chemistry: Vacuum Ultraviolet Spectroscopy as a New Tool for GC Analysis of Terpenes in Flavors and Fragrances
Presenter: Alex Hodgson, VUV Analytics
12:00-14:00Lunch Break, Vendor Seminars, Exhibition & Posters
  Session 13: Green Separations
(Chair: Paul Ferguson)
Session 14: Big Data Chemometrics and Method development (In-Silico) (KVCV)
(Chair: Ken Broeckhoven)
Session 15: Approaches to maximising analytical data (Chair: Scott Fletcher)
14:00 - 14:30 Keynote: 50 shades of Green SFC
Presenter: Caroline West, University of Orleans
Keynote: A paradigm shift for (big) data analysis in chromatography: on the use of Bayesian statistics
Presenter: Gabriel Vivo Truyols, Tecnometrix
Tutorial: Maximising analytical data by understanding the implications of uncertainty
Presenter: Chris Hopley, LGC
14:30 - 14:50 Presentation: Can CE-MS improve the detection of peptides and intact proteins and in biological samples?
Presenter: Stephen Lock, Sciex
Presentation: Chromatographic fingerprints: chemometrics and application in method development
Presenter: Yvan Vanderheyden, Vrije Universiteit Brussel
Presentation: Data to decision: efficient processing of complex petroleomics data
Presenter: Samuel Ellick, University of Bristol
14:50 - 15:10 Presentation: UHPSFC-MS of a Range of Steroidal Compounds
Presenter: Julie Herniman, University of Southampton
Presentation: Use of different computer-aided method development software in late stages across global sites in pharmaceutical industry
Presenter: Kai Chen, Janssen Pharmaceutical Companies of Johnson & Johnson
Presentation: Characterization of Small Heterogeneities in Polymers by Analysis of UPLC/ESI-MS Reconstructed Ion Chromatograms
Presenter: Ruben Epping, Bundesanstalt für Materialforschung und -prüfung (BAM)
15:10 - 15:30 Presentation: Online extraction and determination of carotenoids from food sample by means of supercritical fluid extraction-supercritical fluid chromatography-mass spectrometry
Presenter: Mariosimone Zoccali, University of Messina
Presentation: Structure driven prediction of retention :Improvement of accuracy
Presenter: Roman Szucs, Pfizer
Presentation: Quantitative proteomics for molecular diagnostics of public health
Presenter: Jack Rice, University of Bath
15:30 - 16:00Coffee Break & Exhibition
  Session 16: Ion Mobility - Mass Spectrometry (BMSS) (Chair: Alison Ashcroft) Session 17: Screening Enviroment Pollutants, what can the data tell us? (Chair: Graham Mills) Session 18: Separations by shape: Further applications of chromatography
(Chair: Caroline West)
16:00 - 16:30 Keynote: Ion mobility mass spectrometry - leveraging rich data on the gas-phase ion to separate and assign
Presenter: Cris Lapthorn, GSK
Keynote: Urban water profiling to inform the state of the environment and public health
Presenter: Barbara Kasprzyk-Hordern, University of Bath
Tutorial: Analysis of food products using advanced analytical techniques
Presenter: Paola Dugo, University of Messina
16:30 - 16:50 Presentation: Understanding phosphorylation-mediated effects on NF-κB interactions using IM-MS
Presenter: Claire Eyers, University of Liverpool
Presentation: Suspect screening of aquatic environmental matrices using high resolution analysis and in silico tools for broad scope tentative contaminant identification
Presenter: Leon Barron, King's College London
Presentation: On-line coupling of RPLC and chiral SFC for the analysis of pharmaceutical compounds
Presenter: Marion Iguiniz, Université de Lyon
16:50 - 17:10 Presentation: An Advanced Cyclic Ion Mobility - Mass Spectrometry System
Presenter: Kevin Giles, Waters Corporation
Presentation: Screening of environmental passive sampling extracts using LC Q-TOF-MS in data-independent acquisition mode
Presenter: Anthony Gravell, Natural Resources Wales
Presentation: Enhanced resolution of stereoisomers through Stationary phase optimized selectivity liquid and supercritical chromatography (SOS-LC and SOS-SFC)
Presenter: Ravindra Hegade, Ghent University
17:10 - 17:30 Presentation: FAIMS mass spectrometry for the analysis of peptides and proteins
Presenter: Helen Cooper, University of Birmingham
Presentation: Combining high-capacity sorptive extraction with Thermal desorption pre-concentration for analysis of (S)VOCs in environmental samples
Presenter: Lara Kelly, Markes International Ltd
Presentation: LC-MS/MS chiral ananlysis of chloramphencicol in the environment
Presenter: Felicity Elder, University of Bath
19:15Gala Dinner Event
HTC-15 Conference Programme - Day3 (26th January 2018)
08:55 - 09:00HTC-15 Announcements
09:00 - 09:50 Plenary: Tuulia Hyotylainen - Hyphenated Techniques for comprehensive analysis of all metabolites in biological systems to describe metabolic changes caused by disease, environmental, nutritional, or genetic factors (Lower Hall)
09:50 - 10:30Coffee Break & Exhibition
Time Lower Hall Ferrier Hall Room D
  Session 19: Automating Complex Sample Workflows (Chair: Bob Boughtflower) Session 20: Comprehensive Chromatography - The State of the art (Chair: Hans Gerd Janssen) Session 21: Energy & the Environment
(Chair: Sam Whitmarsh)
10:30 - 11:00 Keynote: Laboratory Automation: The Rise of the Machines
Presenter: Scott Summerfield, GSK
Keynote: Flow Modulated Two-dimensional Gas Chromatography Coupled to Tandem Mass Spectrometry for "Comprehensive" characterization of Complex Samples
Presenter: Luigi Mondello, University of Messina
Tutorial: Environmental health and well-being: diagnostics with hyphenated gas chromatography
Presenter: John Dean, Northumbria University
11:00 - 11:20 Presentation: Automated sample preparation: the missing hyphen to hypernation
Presenter: Camilla Liscio, Anatune
Presentation: Applicability of retention modelling in hydrophilic-interaction liquid chromatography for algorithmic optimization programs with gradient-scanning techniques
Presenter: Bob Pirok, University of Amsterdam
Presentation: Fingerprint characterization of bio-oil from the pyrolysis of African palm and its esterification product
Presenter: Diana Palacio, University of Warwick
11:20 - 11:40 Presentation: Solid Phase Micro-Extraction - Breaking Free from Total Concentration Analysis
Presenter: Sheelan Ahmad, GlaxoSmithKline
Presentation: All Ion Differential Analysis in Product Control Applications using GC/MS and Comprehensive GCxGC/MS
Presenter: Marco Ruijken, MsMetrix
Presentation: Mass Spectrometric Investigation of Compounds of Interest to the Chemical Investigation Programme (CIP) within Environmental Matrices: Homogenate Analysis
Presenter: Rachel Townsend, Swansea University
11:40 - 12:00 Presentation: Analytical developments in sample preparation to reliably measure the emission of volatiles from materials in a high-throughput fashion
Presenter: An Adams, Dow
Presentation: Detection of bacteriologically produced hydrogen sulphide using SHS-MCC-GC-IMS
Presenter: John Dean, Northumbria University
Presentation: Petroleomic Depth Profiling of Staten Island Soil by GC and FT-ICR MS
Presenter: Mary Thomas, University of Warwick
12:00 - 12:40Lunch Break & Exhibition
  Session 22: Analysis of Complex Energy Products (Chair: Tom Lynch) Session 23: Advanced Analysis of Food and Beverages (Chair: Lewis Jones) Session 24: Life science & pharma
(Chair: Melissa Hanna-Brown)
12:40 - 13:10 Keynote: Thermal Analysis in hyphenation with mass spectrometry as a versatile tool for the analysis of complex and high boiling petroleum products
Presenter: Thomas Gröger, helmholtz Zentrum München GmbH
Keynote: Exploiting comprehensive two-dimensional liquid chromatography in food analysis
Presenter: Paola Dugo, University of Messina
Tutorial: LC-MS small molecule quantitation: a short tutorial of best practice
Presenter: Ruth Godfrey, Swansea University
13:10 - 13:30 Presentation: Direct infusion MS - who needs hyphenation anyway?
Presenter: Sam Whitmarsh, BP
Presentation: Can Gas Chromatography - Olfactometry Determine the Importance of Volatile Organic Chemical to Food and Beverage Odour?
Presenter: Lewis Jones, Sensient Flavours
Presentation: From GC-MS to LC-MS/MS: Further Advances in Adrenal Cancer Diagnosis
Presenter: Angela Taylor, University of Birmingham
13:30 - 13:50 Presentation: Fast and efficient group-type analysis of hydrocarbons by GCxGC
Presenter: Laura McGregor, SepSolve Analytical
Presentation: Rapid evaporative ionization mass spectrometry for high throughput screening in food analysis: the case of boar taint
Presenter: Sara Stead, Waters Corporation
Presentation: Green Bioanalytical Analysis of Voriconazole and Tadalafil by HPLC
Presenter: Aysegul Dogan, Hacettepe University
13:50 - 14:10 Presentation: Recent Advances in the Analysis of Petroleum-based Fuels using Gas Chromatography-Vacuum Ultraviolet Spectroscopy
Presenter: James Diekmann, VUV Analytics
Presentation: Monitoring the effect of post-harvest storage on fruit quality by TD-GC×GC-TOF MS
Presenter: Natasha/D. Spadafora, University of Calabria/Markes International
Presentation: Improving Untargeted Metabolomics with Ion Chromatography-Mass Spectrometry
Presenter: John Walsby-Tickle, University of Oxford
14:10 - 14:30Flash Poster Presentations
14:30 - 15:20Of mice, sex and mass spectrometry Plenary by Rob Beynon (Chair: John Langley) (Lower Hall)
15:20 - 16:10Multi-dimensional liquid chromatography of complex mixtures Plenary by Peter Schoenmakers (Chair: Frederic Lynen) (Lower Hall)
16:10 - 16:30Awards
16:30Farewell Event