| Abstract Title: | Analysis of Pesticides, pharmaceuticals and personal care products in drinking and environmental water by Direct Injection Using UHPLC-MS/MS |
| Presenter Name: | Mr Janitha De Alwis |
| Co-authors/Co-presenters: | Dr Claudia Rathmann |
| Company/Organisation: | Waters Corporation |
| Country: | United Kingdom |
Abstract Information :
Monitoring for harmful substances in drinking and environmental water is essential for protecting human health and maintaining good environmental quality standards. Making accurate measurements at ultra- low levels is an essential part of any monitoring program. As more and more pesticides, pharmaceuticals and personal care products (PPPCP) are released into the environment, there is a growing demand for analytical methods with multiple compound groups. The purpose of this work was to demonstrate a direct injection UHPLC-MS/MS method for the ultra-low level determination pesticides, pharmaceuticals and personal care products in drinking and environmental waters. The method performance study was completed on an ACQUITYTM Premier LC System with a XevoTM TQ Absolute Mass Spectrometry System. A method validation study was carried out on drinking water and 2 environmental water matrices. The method performance was assessed using 3 spike levels at 10, 20, and 100 ng/L for all analytes, with 6 replicates at each level. Average method performance for trueness, repeatability, linearity, and sensitivity was assessed through inter and intra-laboratory studies. Using direct injection on Xevo TQ Absolute System removes sample preparation and enables a simple, high-throughput analysis of PPPCP in drinking and environmental waters.
